AIO Circle
The world is not waiting.
Neither should we.
AIO 2026:
Applied Intelligence in Operations
Breakthrough science continues to advance.
Scale is where it is tested - under regulatory pressure, operational constraint and time.
These decisions are being made today.
Often with limited precedent.
Always with consequence.
The gap does not close with technology alone.
It closes with people who know how to apply judgement early, deliberately and when it counts.
Ambition is not the risk.
Scale without discipline is.
Chaired by
Dr Uwe Gottschalk
Operating Partner, Keensight Capital
Former CSO, Lonza Group
A leader in large-scale biomanufacturing, tech transfer and operational build-out across regulated environments.
Why AIO matters
Most organisations succeed in discovery.
The hard part comes later — when volume increases, expectations tighten and operations must hold.
74% of FDA rejections trace to manufacturing. Not the molecule. The manufacturing.
Whether scaling cell and gene therapy, industrial biologics or cultivated protein manufacturing, similar pressures surface:
Release under scrutiny.
Validation at volume.
Trust in data when decisions are irreversible.
AIO exists to convene leaders who have already lived that reality.
Not to pitch. To exchange what worked, what failed and what they would do differently next time.
Featuring
Advisory Circle.
The Few Who Lead | GBX Advisory & Keynote Speakers
Circle Partners
AIO is Curated for
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Chief Operating Officers - transformation, scale, operating model
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Heads of Manufacturing, MSAT and CMC process design, tech transfer, validation
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Leaders in Data, AI and Automation - digital twins, advanced analytics, manufacturing IT
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Quality and Regulatory Executives - QA, QMS, GxP, regulatory strategy
SVP/VP Technical Operations · Site Heads · Process Development · Digital Manufacturing and Automation · Supply Chain · Quality and Regulatory · CDMO
AIO 2026 | The Four Pillars of Applied Intelligent Operations
1
Data
Creates the basis for decisions leaders can stand behind
How do leaders unlock data they trust when decisions matter?
2
Design
Decisions made early enough to prevent failure later
What choices determine whether pilots endure or stall?
3
Operate
Where work happens under pressure
When responsibility is shared, who owns the outcome?
4
Deliver
Release without delay - for the patient waiting
Which approaches work before pressure forces compromise?
Not buzzwords.
Implementation.
COO · CTO · MSAT · CMC · Supply · Digital · Manufacturing · CDMO
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Why AIO is co-located with MEVO
Next-generation protein manufacturing and advanced therapies are converging -
not in science, but in constraint.
Different industries.
The same pressures.
Scale must be earned before markets, regulators or patients are willing to wait.
AIO is co-located with MEVO because leaders in both rooms are navigating the same reality — readiness, responsibility and durability.
The room
AIO convenes a carefully selected group of senior operators and decision-makers.
Not to just present.
To exchange experience.
If you recognise the questions, you belong in the room.
AIO 2026 · London
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